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Home / Ophtalmology / Etiology and pathogenesis of retinal vein occlusion

Etiology and pathogenesis of retinal vein occlusion

отGP News публикувано на 25.07.202428.02.2025 Ophtalmology
ретинална венозна оклузия

Issue 6/2024

Aptikadir, S., Sivkova, N.
Department of Eye Diseases, Faculty of Medicine, Medical University – Plovdiv University Eye Clinic, UMBAL „St. George“ – Plovdiv

One of the most common causes of unilateral vision loss is retinal venous occlusion (RVO), the second most prevalent retinal vascular disease after diabetic retinopathy. RVO pathogenesis remains controversial and incomplete. The multifactorial pathogenesis of RVO is determined by complex interactions between diverse vascular and inflammatory mediators. Several cytokines, chemokines, and growth factors are involved in the pathogenesis of retinal vein occlusion, but VEGF (vascular endothelial growth factor), which plays a central role in the pathophysiology of retinal vein occlusion, is undoubtedly the most important established mediator of vascular permeability and inflammation.

Key words: retinal vein occlusion, pathogenesis, etiology, retinal vascular occlusive diseases

Аddress for correspondation:
Dr. S. Atpikadir
Department of Eye Diseases, Faculty of Medicine,
Medical University – Plovdiv
15 A, „V. Aprilov”, Blvd.
4002, Plovdiv

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