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Home / Dermatology and Cosmetics / Modern therapeutic agents for psoriasis – a long-awaited reality

Modern therapeutic agents for psoriasis – a long-awaited reality

отGP News публикувано на 11.07.2023 Dermatology and Cosmetics
терапевтични средства за псориазис

Issue 7/2023

Pehlivanov, G., Argirov, A.
MBAL VITA 2 – Sofia

Psoriasis is one of the most common skin diseases. It affects 2 to 3% of Europeans. In Bulgaria, nearly 140,000 people live with psoriasis. It has a genetic origin and affects men and women equally. Today, there is a growing understanding that psoriasis is more than a chronic skin disease and that it is a systemic inflammatory disease. Historically, numerous topical medications, systemic oral and parenteral therapy, phototherapy and thalassotherapy have been used to treat psoriasis patients. None of these therapeutic methods have given a lasting satisfactory result. A qualitatively new stage in the therapy not only of psoriasis, but also of other chronic severe diseases, are biological agents. Biologics are molecules that block specific stages of the inflammatory cascade in psoriasis by attacking either immune T-cells (Th1, Th17) or pro-inflammatory cytokines (TNF-α, Il-17,22, IFN-γ, AMPs).

Key words: psoriasis, treatment of psoriasis, biological agents

Address for correspondence:
Markova, R. 
First Pediatric Consultative Clinic – Sofia 
1404, Sofia
51 “Bulgaria”, Blvd.

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