Issue 11/2025
Vasilev, T.
Children’s Hospital “Ivan Mitev” – Sofia; Department of Pediatrics; Medical University – Sofia
This review summarizes current evidence on the role of glycemic variability and continuous glucose monitoring (CGM) in the context of diabetic neuropathy. Key CGM-derived metrics such as Time-in-Range (TIR), Mean Amplitude of Glycemic Excursions (MAGE), and Glucose Management Indicator (GMI) are analyzed for their prognostic value in type 1 and type 2 diabetes. Several studies demonstrate an association between increased glucose variability and the risk of chronic complications. CGM emerges as a valuable tool for personalized diabetes management and a potential strategy for preventing diabetic neuropathy.
Key words: glycemic variability, diabetic neuropathy, continuous glucose monitoring, TIR, MAGE
Address for correspondence:
Dr. Teodor Vasilev
Clinic of Rheumatology, Children’s Hospital
“Ivan Mitev” – Sofia
11, Аcad. Ivan Geshov, Blvd.
1612, Sofia
e-mail: tvasilev@medfac.mu-sofia.bg