Issue 4/2025
Yunakova1,2,3, M., Todorov1,4, I.
1 SAGBAL „Dr. Shterev“ – Sofia
2 SBALAG Maichin dom – Sofia
3 Bulgarian Association on Sterility and Reproductive Health
4 Burgas State University
“Prof. dr. Asen Zlatarov”- Burgas
The diagnosis of cancer significantly impacts an individual‘s physical and mental health, affecting overall quality of life. Advances in medical diagnostics and oncology have led to increased survival rates, particularly in young adults aged 15-40, where survival has doubled in the past 40 years, especially among women due to higher breast cancer rates. Concerns arise regarding reproductive capabilities, as many young cancer patients require gonadotoxic treatments that threaten future fertility. Thus, fertility preservation consultations are essential prior to commencing cancer treatment. This challenge is heightened for pediatric patients, recognizing the psychological burdens faced by families. The term „oncofertility“ emerged in 2006 to represent the intersection of oncology and reproductive medicine, advocating for strategies to safeguard fertility among cancer patients. Various treatments, including chemotherapy and radiotherapy, can adversely affect fertility differently based on age, diagnosis, and treatment modalities. Fertility preservation methods include freezing eggs, sperm, and ovarian tissue, key for prepubescent individuals. With ongoing advancements in reproductive technology and medicine, timely consultation for fertility preservation is critical for young cancer patients, aiming to enhance quality of life post-treatment and maintain reproductive options.
Key words: Oncofertility, Fertility preservation, Cancer, Gonadotoxic, Survival rates
Address for correspondence:
Yunakova, M.
SAGBAL „Dr. Shterev“ – Sofia
25-31, “Hristo Blagoev”, Str.
1330, Sofia